Welcome back to AIMedily! I’m happy you’re here.

Last month, I went to RehabWeek. An international congress where clinicians, engineers, researchers, and industry come together.

The quality of speakers, posters, and workshops was amazing. I even got to visit the Shirley Ryan AbilityLab.

But what I enjoyed the most was that everyone was open to sharing - and connecting. To work together to improve the quality of life of people with disabilities.

But let’s get started with today’s issue. Are you ready?

🤖AIBytes: AI and prosthetics, Robotic exoskeletons in spinal cord injury, and AI rehab in stroke.

🦾TechTool: One camera - complete gate analysis. A Socially Assistive Walker

🧬AIMedily Snaps: Interesting links

🧩TriviaRX: One question (just for fun)

🤖 AIBytes

A team trained an AI model to create accurate, comfortable, and wearable sockets using a 3D scan of the residual limb.

🔬 Methods

Phase 1 – Building the AI with 3D scans from 116 transtibial amputees. Along with socket designs crafted by skilled prosthetists.

The AI model could predict the shape of an optimal socket based on limb geometry.

Phase 2 – Testing AI in the Real World

Ten patients tested both sockets:

  • manually made socket

  • An AI-designed socket- based on the residual limb, 3D-printed.

The prosthetist, physical therapist, and the user evaluated the performance using:

📊 Results

  • Precision: AI-generated sockets deviated only 2.5 mm from expert designs.

  • Wearability: 8 out of 10 AI sockets were viable.

  • Comfort: Scores matched those of traditional sockets.

  • User/Evaluator Preference: In 2 cases, they preferred the AI design.

🔑Key Takeaways

This study shows that AI can accurately replicate expert-level socket design:

  • Automates the design process without compromising precision.

  • Enables rapid 3D printing—potentially cutting fitting time.

  • Improves access in low-resource or rural areas lacking experienced prosthetists.

🔗  Evaluating the Effectiveness of Transtibial Prosthetic Socket Shape Design Using Artificial Intelligence: A Clinical Comparison With Traditional Plaster Cast Socket Designs. van der Stelt, Merel et al. Archives of Physical Medicine and Rehabilitation, Volume 106, Issue 2, 239- 246. https://doi.org/10.1016/j.apmr.2024.08.026

This meta-analysis explores if Robotic Exoskeleton Gait Training was superior to Conventional Physical Therapy in spinal cord injury (SCI).

🔬Methods

Type: Meta-analysis of 15 randomized controlled trials

Sample: 579 patients with Spinal cord injury (ASIA A–D), ages 26–71

Time Since Injury: 2 months–15 years

Interventions: 3–20 weeks, 2–5 sessions/week

Assessment:

📊Results

  • Walking Speed: No significant difference (p = 0.08)

  • Walking Distance: No significant difference (WMD = -1.83 meters, p = 0.78)

  • Balance: Significantly better in Robotic training (p = 0.04)

  • Functional Scores:

    • WISCI-II: Significant improvement (p = 0.0001)

    • LEMS: Significant improvement (p = 0.0005)

  • Respiratory Function (FEV1): Improved in REGT (p = 0.03)

🔑Key Takeaways

  • Robotic exoskeleton training significantly improves balance, strength, functional independence, and respiratory capacity.

  • Robotic exoskeleton gait training doesn't outperform conventional physical therapy in speed or distance. Especially for chronic patients.

  • In chronic injury, conventional therapy may be better to recover speed.

    .🔗 Liu S, Chen F, Yin J, Wang G, Yang L. Comparative efficacy of robotic exoskeleton and conventional gait training in patients with spinal cord injury: a meta-analysis of randomized controlled trials. J NeuroEng Rehabil. 2025;22:121. https://doi.org/10.1186/s12984-025-01212-6

This comprehensive review explores the integration of AI across stroke rehabilitation. From acute management through chronic recovery.

📌 Key Contributions

AI-enhanced imaging (CT/MRI)

  • Enables early detection of ischemic penumbra, supporting faster, more personalized interventions.

Clinical decision support tools

  • Optimize acute treatments like thrombolysis and endovascular therapy.

Robotic systems & exoskeletons,

  • AI exoskeletons and robotic assistive devices enable adaptive motor training.

    How?  by interpreting patient-specific movement patterns.

  • Real-time feedback loops improve precision and reduce therapist burden.

AR + AI Integration

  • Virtual Reality and Augmented Reality environments powered by AI offer:

    Task-specific and immersive rehab scenarios.

  • Platforms personalize difficulty levels based on performance.

Brain–Computer Interfaces (BCIs)

  • Machine learning models decode neural signals for intention-based movement control in BCI.

  • Applied to upper limb recovery and attention training post-stroke.

Wearables with AI

Provide continuous monitoring and feedback, extending rehab to home settings.

AI-driven tele-rehabilitation

  • Bridges geographic gaps for remote care delivery.

Predictive Analytics

  • AI models can forecast functional recovery. This allows adjustments to therapy and to personalise treatment.

🔑 Key Takeaways

This article outlines a clear vision:

AI is not a replacement for human care.

It is an amplifier of clinical precision, individualized recovery, and healthcare efficiency.

Also flags critical considerations—data privacy, regulatory standards, and ethical implementation—as essential for safe, effective adoption.

🔗 Kopalli SR, Shukla M, Jayaprakash B, et al. Artificial Intelligence in Stroke Rehabilitation: From Acute Care to Long-term Recovery. Neuroscience. 2025 Apr;572:120412. https://doi.org/10.1016/j.neuroscience.2025.03.017.

🦾TechTool

3DGait is an AI enhanced gait analysis system that uses:

  • Single consumer-grade depth camera

  • No markers required

  • No complex setup or calibration

  • No trained personnel needed

⚙️ Technology:

  • Advanced machine learning algorithms

  • Produces 49 gait biomarkers

  • Angular, spatial, and temporal measurements

🔑 Key takeaways

  • Clinically acceptable accuracy vs. traditional systems

  • No markers, calibration, or fixed cameras needed

  • Practical for non-specialist clinics and home use

  • Supports patient monitoring and chronic disease management

🔗 L, Chang R, Wang J, et al. Artificial intelligence-enhanced 3D gait analysis with a single consumer-grade camera. J Biomech. 2025 Jun;187:112738. https://doi.org/10.1016/j.jbiomech.2025.112738

A research team from the University of Bristol developed a socially assistive walker. This device delivers both physical and cognitive support to older adults.

Designed to be affordable and user-friendly.

🔬 Methods

A team of geriatric care professionals co-design the walker.

It was a walker frame with integrated sensors, feedback mechanisms, and a user interface for interactive support.

They tested the walker on healthy adults during daily living activities.

Had two distinct modes:

  • High Engagement: Voice prompts, virtual agent presence, personalized interactions

  • Low Engagement: Text-only instructions, minimal feedback.

📊Results

  • 78.5% preferred the high-interaction mode (p < 0.05). In embodiment, verbal feedback, and proactive cues.

  • Users valued verbal praise, clear instructions, and multimodal feedback.

🔑 Key Takeaways

Social-cognitive features improve patient preference and engagement.

🔗 Haque MR, Yang H, Yoshida T, Tsujita T. (2024). Socially assistive walker: user preferences on low and high interaction modes. Frontiers in Robotics and AI, 11:1401663. doi: 10.3389/frobt.2024.1401663

🧩TriviaRX

Why can't you tickle yourself?

A) Cerebellum predicts self-touch

B) Spinal gate theory

C) Lack of surprise element

D) Motor cortex inhibition

(The answer will be in the next issue)

That's all for today!

If you have articles on AI and Rehabilitation and want to share them, reply to this email 📤.

If you want me to write about a specific topic, make your request!

And one last favor, please share AIMedily with colleagues. I would be forever grateful 🥰 https://www.aimedily.com/

See you next week,

Itzel Fer, MD PM&R

P.S. Follow me on social media LinkedIn | Substack | X

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