Hi!

Today is LLM Friday. A day dedicated to Large Language Models.

Today, I have an important question for you: if I could personally help you solve one problem related to AI, what would that be?

Please, hit reply with your answer. I promise I will read and answer each one of them directly to your email.

Now, grab a drink and let’s dive into today’s issue.

✨LLMs

This study analyzed how 75 healthcare professionals used generative AI to draft replies to patients in their Electronic Health Record (EHR).

Researchers used EHR audit logs from a NYC Langone Health system over 11 months to measure use rates, efficiency gains, and workflow impacts.

🔬 Methods

Participants: 75 HCPs (72% physicians, 19% clinical support, 9% administrative support).

GenAI-drafted responses to patient messages in EHR.

Assessment: Use rates, response time, actions, linguistic analysis of drafts.

📊 Results

  • Overall use: 19.4%. This improved from 12% to 20% after prompt refinements.

  • Administrative staff showed highest adoption (32%), followed by clinical support staff (14%), and physicians (12%).

  • Time savings with AI: 6.76% faster median response time.

  • 7.27% increase in message open time (to review the AI draft added time)

  • 80% of the messages did not receive a response. Reviewing unnecessary drafts increased the burden by 135% compared to reading messages alone.

Successful AI drafts were:

  • Concise, fewer words, but more informative.

  • Highly relevant to patient questions.

  • Easy to read (higher readability scores).

  • More subjective/empathetic.

🔑 Key Takeaways

  • Use differs significantly with role. Messages need to be tailored based on professional needs.

  • Concise and relevant responses are more likely to be used.

  • GenAI can accelerate message response time.

  • Drafts need to be generated only for messages requiring responses.

  • Prompts need to be refined based on use patterns.

  • Aligning AI tools with existing clinical processes needs to be considered.

🔗Mandal S, Wiesenfeld BM, Szerencsy AC, et al. Utilization of Generative AI-drafted Responses for Managing Patient-Provider Communication. npj Digital Medicine. 2025;8:591. https://doi.org/10.1038/s41746-025-01972-w

🦾TechTools

Last week, we talked about different prompting styles.

Now, when you give prompts to AI this week, try adding these quick details:

  1. Who you want the LLM to be: If you want a physician, PT, or OT’s opinion, be specific.

  2. S: Age, signs and symptoms, clinical history of the patient.

  3. O: Patient’s age, vitals, physical exam findings, test results.

  4. A: A possible diagnosis, differential diagnosis (ask for orientation if you need it).

  5. P: Treatments (ask for official guidelines).

You’ll see the jump from generic advice → clinically relevant information.

Let me know your results.

That’s all for today.

You’re already ahead of the curve in medical LLMs — don’t keep it to yourself. Forward AIMedily to a colleague who’d appreciate the insights.

Thank you!

Until next Wednesday.

Itzel Fer, MD PM&R

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